![]() The technology of continuous autofocusing can result in different areas of the slide being out of focus but lower rates of WSI completely out of focus in comparison to scanners using focus points. Tissue can be either entirely or only partially out of focus. Software, hardware and slide-related issues may all contribute to interruptions.Īfter quality control check, establish the proportion of slides that need to be rescanned (e.g., due to focus issues and missing tissue). The vulnerability to interruptions is one of the most important aspects of scanner performance and can have an especially profound impact on overnight scanning. In our experience, scan times may vary up to a minute per slide on different scanners at the same magnification. resections) and the number of pathologists to be signing out cases digitally. The scanning speed can be a bottleneck in the diagnostic workflow depending on the number of slides, the type of specimen (biopsies vs. Scan time at 40× magnification and for dayload The most complex application is the digitization and storage of whole slides images (WSI), either for use in diagnostic routine or for educational or research purposes.įile sizes can vary considerably (up to over fourfold) among different scanners and will therefore have a major impact on the storage space needed. Real-time sharing of pathology images with a common viewer (telepathology) has been favored for some time by hospital systems with multiple sites and increasingly implemented during the COVID-19 pandemic ( 6). For instance, digital photography to capture and store macroscopic images can be considered one of the first widespread aspects of digital pathology. What constitutes digital pathology? Broadly interpreted, this can entail any sort of work involving a digital image. Select review articles, white papers and consensus guidelines are recommended for further in-depth reading ( 1– 5). The objective of this article is to provide a broad overview of digital pathology for the general pathologist and address real-world issues which may be underrepresented in the literature. Careful planning and certain practical considerations can be paramount for a smooth transition to an efficient digital workflow. As technical aspects and possibilities advance at nearly dizzying speed, it must be emphasized that a digital approach will affect many fundamental aspects of daily routine in a pathology lab. However, many pathology institutes that pursue the path to digital pathology realize that this is not always as straightforward as it seems. ![]() In many parts of the world, at least part of pathologists’ work has become “digital,” i.e., conventional routine replaced by digital images.
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